Additionally, TGF-β-induced EMT appears to be crucial for the induction and maintenance of cancer stem cells; in particular, an increase in CD44high/CD24low breast cancer stem cells, recognized for their high tumorigenic potential [30, 31], together with significant cell migration and invasion in lung adenocarcinoma [32] and an increased probability of mesenchymal phenotype acquisition in hepatocarcinoma cells [33], was noted. This evidence concerns the gene TGFB1 and cancer.