This analysis, in combination with stringent filtering, allowed identification of 16 prioritized candidate loci in CLL (Fig. 5b; Additional file 1: Fig. S5.1a, b), which include previously implicated genes such as CTLA4 and WNT3 [73, 74] (Fig. 5b). This evidence concerns the gene WNT3 and B-cell chronic lymphocytic leukemia.