We observed enrichment of many similar types of TFs, related to B cell function such as IRF, RUNX, and EBF1 (Additional file 1: Fig. S5.2e, f), but also specific enrichment of factors such as FOXO1 (as also seen for rs895555) in CLL which have been implicated in CLL and harbor driver mutations [75]. The gene discussed is FOXO1; the disease is B-cell chronic lymphocytic leukemia.