LPA and cancer: Therefore, to comprehensively explore the association of the combination of Lp(a) and FIB with all-cause, CVD, and cancer-related mortality, we conducted this study and found that high levels of both Lp(a) and FIB together conferred a 1.8-fold risk of all-cause mortality, a 2.1-fold risk of CVD-related mortality, and a 2.4-fold risk of cancer-related mortality compared with low levels of both Lp(a) and FIB.