IRF1 and non-small cell lung carcinoma: Another study used quantitative reverse transcription polymerase chain reaction (RT-qPCR) to detect the relationship between four target immune genes, CD274, programmed cell death 1 ligand 2 (PDCD1LG2), CD8A and interferon regulatory factor 1 (IRF1), and ICIs treatment response in 122 patients with advanced NSCLC.