HDAC1 and polycystic ovary syndrome: Plumbagin, quercetin, HDAC1 (histone deacetylase 1), leonurine hydrochloride, certain Chinese traditional medicine recipes (Bushenhuoluo decoction (BSHLD), Bushen Cuyun recipe and He’s Yang Chao recipe), α-ketoglutarate, human bone marrow derived-mesenchymal stem cells (hBMSCs), metformin, genipin, tauro-ursodeoxycholic acid (TUDCA), cysteine-rich 61 (CYR61) and cyproterone acetate have been found to suppress pyroptotic death of GCs in different model systems of POI and PCOS.