H19 and polycystic ovary syndrome: HDAC1 suppresses the pyroptosis of GCs in PCOS through deacetylation of H3K9ac on the lncRNA H19 promoter to regulate the H19 / miR-29a-3p / NLRP3 axis, as shown in in vitro PCOS cell models (dihydrotestosterone (DHT)-induced HGL5 cells) [26].