Normally, the upregulation of WTAP (a key regulator of RNA N6-methylase complex) results in the overactivation of the inflammasome in GCs, since WTAP stabilizes ASC (a NLRP3 inflammasome component) mRNA by mediating its N6-methylation in GCs from the PCOS model. This evidence concerns the gene WTAP and polycystic ovary syndrome.