MADD and neoplasm: Next, we examined the PPHLN1 (exon 6, chr12:42778741–42778798) and MADD (exon 26, chr11:47330530–47330593) splicing patterns across a variety of tumour types (The Cancer Genome Atlas (TCGA)) and normal tissues (Genotype-Tissue Expression (GTEx)) (Fig. 7a–d).