The evidence base is considered strong in the commonest subtypes of monogenic diabetes such as glucokinase (GCK)-related hyperglycemia, Hepatic Nuclear Factor 1 alpha (HNF1A)-diabetes, and ATP sensitive potassium channel (KATP)-neonatal diabetes (ND, related to pathogenic variants in KCNJ11 and ABCC8). This evidence concerns the gene GCK and Norrie disease.