PRKG1 and anal carcinoma: Proteins like Acca (acetyl-CoA carboxylase carboxyl transferase subunit alpha), glyA (glycine hydroxymethyltransferase), glyQ (glycyl-tRNA synthetase alpha chain), eno (enolase), pgk (phosphoglycerate kinase), and por (pyruvate-ferredoxin/flavodoxin oxidoreductase) were previously identified in anal samples from individuals with precancerous anal lesions (10), underlining their potential roles as metabolic markers in anal cancer progression.