DDR1 and breast cancer: Since DDR1 mutation has also been demonstrated to be positively correlated with poor prognosis in breast cancer,[22] we analyzed DDR1 mutations based on cBioPortal and a GC cohort from our center.[23, 24] However, only 14 mutations were found in 534 patients in cBioPortal (Figure 1e), and we found 13 S495S mutations, suggesting that mutation might not be the primary contributor to GC progression (Figure 1f).