In comparison with control mice that received isotype antibodies, IL-17A neutralization in mice infected with the low-virulence M. bovis strain 534 from Days 6 to 12 post-infection, when the highest IL-17A production in the lung was seen, did not affect mouse survival but produced a significant increase in bacillary burdens after seven days of infection and a non-significant decrease in inflammatory infiltrated and granuloma areas (Fig 6). Here, IL17A is linked to infection.