CD8A and myocarditis: In a multi-omics analysis of peripheral blood mononuclear cells (PBMCs) from patients with ICI myocarditis, an expansion of the cytotoxic Temra CD8+ T cells (re-expressing CD45RA) was found compared to controls, with increased expression of pro-inflammatory chemokines (e.g., CCL5, CCL4, CCL4L2).