KEGG pathway analysis indicated that DEGs were mainly enriched in the Wnt signaling pathway, AGE-RAGE signaling pathway in diabetic complications, alcoholic liver disease, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, glutathione metabolism, non-alcoholic fatty liver disease, and ovarian steroidogenesis, etc. (Fig. 2D). This evidence concerns the gene RENBP and alcoholic liver diseases.