miR-361-3p was reported to be significantly elevated in sEVs derived from hypoxic colorectal cancer (CRC) cells, and when transferred to normoxic CRC cells, it facilitates cell growth and suppresses cell apoptosis, by targeting TNF receptor-associated factor 3 and consequently activating the noncanonical NF-κB pathway [91]. Here, TRAF3 is linked to colorectal carcinoma.