RFC1 and cerebellar ataxia: Recently, rare variants in MME were detected in both familial and non-familial cases of chronic idiopathic axonal polyneuropathy (7, 28), and repeat expansions of RFC1 in patients with a complex phenotype (sensory neuropathy, cerebellar ataxia and vestibular disturbance) and also in patients with idiopathic sensory neuropathy although with time this may evolve to the more complex phenotype (30, 31).