For instance, C-reactive protein (CRP) and other inflammatory markers have shown some predictive value but are often influenced by a range of non-cardiac factors, leading to potential inaccuracies [5]. In contrast, NT-proBNP has consistently demonstrated a stronger association with cardiac stress and AF onset, justifying our focus on this biomarker as a superior predictive tool [6]. The gene discussed is CRP; the disease is atrial fibrillation.