The PPV for TB increased from 34.7% to 40.0%, 41.2%, and 45.7% as the CRP threshold increased from ≥1 mg/L, to ≥3 mg/L, ≥ 5 mg/L, and ≥10 mg/L, respectively, and the NPV decreased from 91.5% to 88.9%, 86.0%, and 85.5%. The gene discussed is CRP; the disease is tuberculosis.