TRPA1 and dyspepsia: This extensive exploration delves into the profound and complex links between TRPA1 dysregulation and gastrointestinal maladies, including Irritable Bowel Syndrome (IBS) (Choi et al., 2023), Inflammatory Bowel Disease (IBD) (Cseko et al., 2019), and Functional Dyspepsia (Balemans et al., 2017), comprehensively illustrating how aberrant TRPA1 signaling contributes to the complexity of these disorders.