In addition, KEGG enriched results showed that PDCD2 was mainly involved in cell cycle, pyrimidine metabolism, purine metabolism, endocytosis, focal adhesion, Huntington's disease, JAK/STAT signaling pathway, MAPK signaling pathway, chemokine signaling pathway, pathways in cancer, regulation of actin cytoskeleton, and ribosome (Fig. 11A–C). The gene discussed is PDCD2; the disease is juvenile Huntington disease.