We found that PDCD2 expression was increased in bladder urothelial carcinoma (BLCA), stomach adenocarcinoma (STAD), cholangiocarcinoma (CHOL), colon adenocarcinoma (COAD), glioblastoma multiforme (GBM), rectum adenocarcinoma (READ), liver hepatocellular carcinoma (LIHC), lung adenocarcinoma (LUAD), esophageal carcinoma (ESCA), lung squamous cell carcinoma (LUSC), prostate adenocarcinoma (PRAD), breast invasive carcinoma (BRCA), and uterine corpus endometrial carcinoma (UCEC) tissues compared with adjacent normal tissues. This evidence concerns the gene PDCD2 and carcinoma of esophagus.