Perilla seed oil, rich in α-linolenic acid, reduces colitis by suppressing inflammatory markers including interleukin-1 (IL-1), interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-5 (IL-5), interleukin-6 (IL-6), and interleukin-10 (IL-10) [65,54]. Here, IL4 is linked to colitis.