DEPs in the study such as epoxide hydrolase 4 (EH4), neurolysin, histone-H 3, GNB 5, Aβ, calsyntenin-3, myoglobin, metallothionein-1, and neurogranin have also been reported to be directly or indirectly associated with AD or Aβ [[56], [57], [58], [59], [60], [61]]. The gene discussed is EPHX4; the disease is Alzheimer disease.