Moreover, formononetin (Zhang et al., 2023), protocatechualdehyde (Ding et al., 2024), and mulberry leaves flavonoids (Yang and Cao, 2022) have shown significant effects in alleviating DCM by a mechanism related to the inhibition of the NLRP3 signaling pathway. This evidence concerns the gene NLRP3 and familial dilated cardiomyopathy.