TGFB1 and Myocardial fibrosis: Moreover, Soy isoflavone (Huang et al., 2023), Zicui Tongmai Yin (Wu et al., 2021), ginkgolide B (Gao and Hou, 2022), and echinacoside (Liao et al., 2022) have shown significant effects in alleviating myocardial fibrosis in diabetes by a mechanism related to the inhibition of the TGF-β/Smad signaling pathway.