In bladder cancer cells, erianin evoked ferroptosis by inducing NRF2 inactivation characterized by decreased FTH1, GPX4, HO-1, and xCT/SLC7A11 expression as well as the accumulation of ROS and the depletion of GSH (Xiang et al., 2021). The gene discussed is FTH1; the disease is urinary bladder cancer.