In bladder cancer cells, erianin evoked ferroptosis by inducing NRF2 inactivation characterized by decreased FTH1, GPX4, HO-1, and xCT/SLC7A11 expression as well as the accumulation of ROS and the depletion of GSH (Xiang et al., 2021). This evidence concerns the gene FTH1 and urinary bladder carcinoma.