It has been reported that the PTX-3 level of patients with acute coronary syndrome increases by about 6–7 ng/mL (21, 22), the PTX-3 level of patients with congestive heart failure increases (about 3–4 ng/mL) (23), the PTX-3 level in renal failure increases by about 5–6 ng/mL (14, 24), and the PTX-3 level in acute respiratory distress syndrome increases by about 70 ng/mL (25). This evidence concerns the gene PTX3 and Renal insufficiency.