Among sepsis patients, the maximum PTX-3 value of non-surviving patients in the first to fourth days is significantly higher than that of surviving patients (44.8 vs. 6.4 ng/mL, P<0.001), and the AUC for predicting the case fatality rate is 0.82 (cut-off value 15 ng/mL, sensitivity 72%, specificity 81%) (51). This evidence concerns the gene PTX3 and Sepsis.