SLC38A7 and cancer: These amino acid transporters are closely involved in glutamine/glutamate metabolism and mTORC1 signaling, which are key mechanisms of reduced glutathione and ATP production.50 Therefore, the indirect targeting of mTORC1, which is closely associated with the nonselective autophagy pathway, with amino acid transporter and autophagy inhibitors represents a promising treatment option for refractory cancers, including resistant dormant cells.51