SQSTM1 and Alzheimer disease: In HeLa and MCF-7 cells, the expressions of the autophagosome marker LC3-II (Figure 1a,b,e,f; Supplementary Figure S1a,b,e,f) and selective MA receptor p62/SQSTM1 (p62) (Figure 1c,d,g,h; Supplementary Figure S1c,d,g,h) were reduced to ≤ 50% at the time of or 5 h after extracellular AD.