HLA-DRB1 and infection: In the case of pigs, among the GO terms represented from DEPs, “Antigen processing and presentation” and “Structural constituent of cytoskeleton” were found, sharing the protein major histocompatibility complex class II, DR beta 1 (HLA-DRB1), which is directly involved in the processing and presentation of mycobacterial antigens, crucial to control this infection (64).