Indeed (Fig. 2), a strong correlation was observed between spot PCR and urinary sCD163/creatinuria ratio in LN-A patients (PCR median: 1417 ng/mmol [IQ: 581–4120]; Spearman's rho = 0.774, p < 10−4), in LN-IR patients (PCR median: 98 ng/mmol [IQ: 44–186]; rho = 0.487, p = 0.05), and in non-LN patients (PCR median: 52 ng/mmol [IQ: 10.5–131]; rho = 0.608, p < 10−4). This evidence concerns the gene CD163 and lobular neoplasia.