At 100 % specificity, the threshold was 37.5 ng for total sCD163 (sensitivity of 4 % versus LN-IR and 19.5 % versus non-LN), and 2.2 ng/g for the sCD163/proteinuria ratio (sensitivity of 22 % versus LN-IR and 39 % versus non-LN). Here, CD163 is linked to lobular neoplasia.