The ROC curves between LN-A with LN-IR and between LN-A with non-LN patients were further used to demonstrate that sCD163/creatinuria ratio performances were higher than those obtained with the spot urine PCR (AUC = 0.989 and 0.951, respectively), the unnormalized value of sCD163 (sCD163 total, AUC = 0.946 and 0.938, respectively), and even more with the sCD163 normalized to proteinuria (AUC = 0.723 and 0.775, respectively) (Fig. 1E/F). The gene discussed is CD163; the disease is lobular neoplasia.