HDAC3 and Cerebral ischemia: There is evidence that HDAC3 stimulates the formation of pro-inflammatory microenvironment by regulating the cyclic GMP-AMP synthase (cGAS)-stimulator of the interferon genes (cGAS-STING) pathway, whereas the inhibition of HDAC3 attenuates cerebral ischemia/reperfusion-induced brain damage and neuroinflammation [107].