PLIN3 and neoplasm: To further elucidate the role of METTL14 in promoting the malignant progression of NPC, we examined the expression of PLIN3 (a lipid droplet marker) in subcutaneous tumours (Figure S11A) and lung metastatic tissues (Figure S11B), and IHC data confirmed that lipid levels were higher in the METTL14 overexpression group and lower in the METTL14 knockdown group compared to the control group.