Overexpression of ANKRD22 promoted the migration (Figure S3I,J), invasion (Figure S3J), proliferation (Figure S3K) and colony formation capability (Figure S3L) of NPC cells, while knockdown of ANKRD22 significantly inhibited NPC cells migration, invasion, proliferation and colony formation capability (Figure S3 I, J, K, L), aligning with the phenotypes observed with METTL14 overexpression or knockdown. The gene discussed is ANKRD22; the disease is nasopharyngeal carcinoma.