ALKBH3 and neoplasm: The study of tRNA m3C demethylases is still not very clear, but there is a small amount of evidence pointing to demethylation of tRNA m3C, but the reversion of tRNA m3C levels by ALKBH3 deletion is not very significant, while ALKBH3 supports tumor cell growth and is localized in the nucleus, which makes whether ALKBH3 regulates tumor cell growth through tRNA m3C demethylation-dependent manner is still one of the scientific questions worth investigating [76–78].