So far, repeat expansion in five different genes have been identified as causative of OPDM: GIPC1, LRP12, NOTCH2NLC, and most recently, RILPL1 and ABCD3, along with a noncoding CGG repeat expansion in LOC642361/NUTM2B-AS1 [27,28,29▪▪,30▪,31]. Here, RILPL1 is linked to oculopharyngodistal myopathy.