IL18 and lung disorder: IL‐1β, an essential component of inflammasomes, is host‐protective against various pathogens (Lopez‐Castejon & Brough, 2011; Rastogi & Briken, 2022). Compared with PBMC from healthy household controls, stimulated PBMC of NTM lung disease subjects had reduced production of IL‐1 family of cytokines (IL‐1α, IL‐1β, and IL‐18) (Jung et al., 2022).