In addition, Wang et al. established a prognostic model for five genes (TNFRSF14, NFKBIA, DLG3, IRF2 and CYP27A1) based on the cell immune related gene module in TCGA-BRCA, which can effectively predict the prognosis and immune model of breast cancer patients (Wang et al., 2023). Here, CYP27A1 is linked to breast cancer.