The same two unreported mutations (c.3592_3628 + 45del, p? and c.11207 T > C, p.(Ile3736Thr)) in the fetal PKHD1 gene (NM_138694.4) were identified inherited from the parents in our study, where related phenotypes of two fetuses showed recurrent enlarged echogenic of polycystic kidney and oligoamnios. This evidence concerns the gene PKHD1 and oligohydramnios.