KEGG heatmaps revealed significant enrichment in tumor suppressor pathways (including p53, Mismatch Repair) and liver cancer stem cell signaling (Notch, Wnt) in the low-risk group, while the high-risk group was enriched in cancer-promoting pathways like tryptophan and phenylalanine metabolism (Figure 5G). The gene discussed is TP53; the disease is neoplasm.