Neutrophils are recruited to sites of infection by inflammatory cytokines, particularly the chemokine CXCL8 [murine homologues are keratinocyte chemoattractant (KC) and macrophage-inflammatory protein 2 (MIP-2)], which binds CXCR1 and CXCR2 receptors on neutrophils (173–175). This evidence concerns the gene CXCL8 and infection.