Within NSCLC, the most commonly targeted antigens encompass EGFR, mesothelin (MSLN), mucin 1 (MUC1), prostate stem cell antigen (PSCA), carcinoembryonic antigen (CEA), PD-L1, CD80/CD86, inactive tyrosine-protein kinase transmembrane receptor (ROR1), and human EGFR2 (82). The gene discussed is MSLN; the disease is non-small cell lung carcinoma.