Circ‐RNAs (circ‐SHKBP,111 circRNA‐100338112) in tumor exosomes can act as ceRNAs to inhibit miR‐877‐3p, thereby increasing VEGFA expression,111 and can also regulate angiogenesis by interacting with the RNA‐binding protein NOVA2.112. The gene discussed is VEGFA; the disease is neoplasm.