CASP1 and epilepsy: As a key component of inflammasome signaling, caspase-1 is well placed to influence post-traumatic epilepsy through the activation of several downstream products, including, for example, IL-1β, Gasdermin D, and IL-18 another pro-inflammatory cytokine released from a variety of cells such as monocytes, macrophages, and keratinocytes [78].