Conversely, an increase in Myeloid Dendritic Cells (OR = 1.05 [1.01,1.09], P = 0.012), CD14 + CD16 + monocytes (OR = 1.08 [1.01,1.14], P = 0.018), CD8 + T cells (OR = 1.04 [1.01,1.08], P = 0.014), and CD127- CD8 + T cells (OR = 1.08 [1.01,1.16], P = 0.025) was associated with an increased incidence of chronic periodontitis. The gene discussed is IL7R; the disease is chronic periodontitis.