However, the treatment of STZ-induced T1DM mice with adoptively transferred nBMCs and adoptively transferred dBMCs led to significant reduction in the level of IAA, comparing to that in STZ-induced T1DM mice treated with insulin (11.20 ± 0.90 pg/mg and 14.67 ± 0.80 pg/mg, respectively versus 22.20 ± 1.40 pg/mg) (Fig. 5B). The gene discussed is INS; the disease is type 1 diabetes mellitus.