INS and type 1 diabetes mellitus: Moreover, the injection of STZ-induced T1DM mice with sodium citrate buffer, insulin and adoptively transferred dBMCs significantly decreased the serum level of IL-6 comparing to that in naive mice received sodium citrate buffer (153.93 ± 5.08 pg/ml, 105.77 ± 4.05 pg/ml and 61.63 ± 7.35 pg/ml, respectively versus 43.47 ± 2.60 pg/ml) (Fig. 4F).