On the other hand, the treatment of STZ-induced T1DM mice with insulin or adoptively transferred nBMCs significantly increased the total splenocytes count comparing to that in STZ-induced T1DM mice treated with sodium citrate buffer (6.70 ± 0.40 × 106 and 8.70 ± 0.20 × 106, respectively versus 4.70 ± 0.40 × 106) (Fig. 3). The gene discussed is INS; the disease is type 1 diabetes mellitus.