INS and type 1 diabetes mellitus: Additionally, the treatment of STZ-induced T1DM mice with insulin, adoptively transferred nBMCs and adoptively transferred dBMCs resulted in significant increase in the level of ZenT8 comparing to that in STZ-induced T1DM mice received sodium citrate buffer (0.97 ± 0.08 pg/mg, 2.30 ± 0.05 pg/mg and 1.36 ± 0.03 pg/mg, respectively, respectively versus 0.47 ± 0.05 ng/mg) (Fig. 5C).