Furthermore, the administration of STZ-induced T1DM mice with insulin, adoptively transferred nBMCs and adoptively transferred dBMCs led to significant increase in the level of serum SOD comparing to that in STZ-induced T1DM mice received sodium citrate buffer (119.5 ± 2.12 nmol/ml, 121 ± 1.00 nmol/ml and 81.5 ± 2.50 nmol/ml, versus 119.5 ± 1.50 nmol/ml) (Fig. 7C). This evidence concerns the gene SOD1 and type 1 diabetes mellitus.