INS and type 1 diabetes mellitus: The administration of STZ-induced T1DM mice with adoptively transferred nBMCs significantly increased the level of serum insulin, while their administration with adoptively transferred dBMCs significantly decreased the level of serum insulin when compared to that in STZ-induced T1DM mice received insulin (0.46 ± 0.07 μU/ml and 0.22 ± 0.02 μU/ml, respectively versus 0.41 ± 0.4 μU/ml) (Fig. 2B).