INS and type 1 diabetes mellitus: The inoculation of STZ-induced T1DM mice with adoptively transferred nBMCs and adoptively transferred dBMCs resulted in significant reduction in the level of ICA comparing to that in STZ-induced T1DM mice treated with insulin (0.79 ± 0.01 pg/mg and 1.12 ± 0.07 pg/mg, respectively versus 2.01 ± 0.08 pg/mg) (Fig. 5A).