The treatment of STZ-induced T1DM mice with adoptively transferred nBMCs led to significant increase in the total count of leucocytes, while their treatment with adoptively transferred dBMCs resulted in significant decrease in the total count of leucocytes comparing to that in STZ-induced T1DM mice treated with insulin (8.35 ± 0.35 × 103 and 4.45 ± 0.15 × 103, respectively versus 6.25 ± 0.15 × 103) (Fig. 9A). This evidence concerns the gene INS and type 1 diabetes mellitus.