INS and type 1 diabetes mellitus: The data here revealed that the treatment of STZ-induced T1DM mice with sodium citrate buffer, insulin and adoptively transferred dBMCs significantly increased the serum level of TGF-β comparing to that in naive mice received sodium citrate buffer (146.67 ± 9.56 pg/ml, 99.47 ± 3.98 pg/ml, 32.53 ± 2.00 pg/ml and 27.96 ± 2.40 pg/ml, respectively versus 23.43 ± 2.10 pg/ml) (Fig. 4C).