Our results revealed that the treatment of STZ-induced T1DM mice with sodium citrate buffer, insulin and adoptively transferred dBMCs significantly decreased the relative % of granulocytes comparing to that in naive mice received sodium citrate buffer (3.40 ± 0.10, 4.10 ± 0.30 and 3.45 ± 0.45%, respectively versus 9.10 ± 0.20%) (Fig. 9C). Here, INS is linked to type 1 diabetes mellitus.