The injection of STZ-induced T1DM mice with adoptively transferred nBMCs or adoptively transferred dBMCs significantly increased the serum level of IL-10 comparing to that in STZ-induced T1DM mice treated with insulin (223.13 ± 6.75 pg/ml and 183.93 ± 7.34 pg/ml, respectively versus 152.33 ± 5.05 pg/ml) (Fig. 4G). This evidence concerns the gene INS and type 1 diabetes mellitus.