On the other hand, the administration of STZ-induced T1DM mice treated with sodium citrate buffer, insulin, adoptively transferred nBMCs and adoptively transferred dBMCs significantly decreased the level of serum insulin comparable to naïve mice received sodium citrate buffer (0.20 ± 0.01 μU/ml, 0.41 ± 0.40 μU/ml, 0.46 ± 0.07 μU/ml and 0.22 ± 0.02 μU/ml, respectively versus 0.61 ± 0.17 μU/ml) (Fig. 2B). The gene discussed is INS; the disease is type 1 diabetes mellitus.