INS and type 1 diabetes mellitus: The injection of STZ-induced T1DM mice with adoptively transferred nBMCs or adoptively transferred dBMCs significantly decreased the serum level of IL-6 comparing to that in STZ-induced T1DM mice treated with insulin (41.83 ± 6.96 pg/ml and 61.63 ± 7.35 pg/ml, respectively versus 105.77 ± 4.05 pg/ml) (Fig. 4F).