Furthermore, the injection of STZ-induced T1DM mice with insulin, adoptively transferred nBMCs and adoptively transferred dBMCs resulted in significant increase in the level of (GAD comparing to that in STZ-induced T1DM mice received sodium citrate buffer (41.33 ± 1.76 pg/mg, 87.70 ± 2.55 pg/mg and 60.10 ± 1.42 pg/mg, respectively versus 13.33 ± 2.19 pg/mg) (Fig. 5D). This evidence concerns the gene INS and type 1 diabetes mellitus.