Additionally, the data here showed that the administration of STZ-induced T1DM mice with sodium citrate buffer, insulin, adoptively transferred nBMCs or adoptively transferred dBMCs significantly decreased the level of serum SOD comparing to that in naive mice received sodium citrate buffer (65.5 ± 1.50 nmol/ml, 119.5 ± 1.50 nmol/ml, 121 ± 1.00 nmol/ml and 81.5 ± 2.50 nmol/ml, respectively versus 136.0 ± 2.00nmol/ml) (Fig. 7C). The gene discussed is SOD1; the disease is type 1 diabetes mellitus.