INS and type 1 diabetes mellitus: The administration of STZ-induced T1DM mice with adoptively transferred nBMCs or adoptively transferred dBMCs resulted in significant increase in the level of IA-2 comparing to that in STZ-induced T1DM mice treated with insulin (0.84 ± 0.002 pg/mg and 0.57 ± 0.01 pg/mg, respectively versus 0.42 ± 0.01 pg/mg ng/mg) (Fig. 5E).