INS and type 1 diabetes mellitus: The inoculation of STZ-induced T1DM mice with insulin, adoptively transferred nBMCs and adoptively transferred dBMCs significantly decreased the serum level of IL-6 comparing to that in STZ-induced T1DM mice received sodium citrate buffer (105.77 ± 4.05 pg/ml, 41.83 ± 6.96 pg/ml and 61.63 ± 7.35 pg/ml, respectively versus 153.93 ± 5.08 pg/ml) (Fig. 4F).