However, the treatment of STZ-induced T1DM mice with adoptively transferred nBMCs or adoptively transferred dBMCs resulted in significant increase in the level of ZenT8 comparing to that in STZ-induced T1DM mice treated with insulin (2.30 ± 0.03 pg/mg and 1.36 ± 0.03 pg/mg, respectively versus 0.97 ± 0.08 pg/mg) (Fig. 5C). Here, INS is linked to type 1 diabetes mellitus.