INS and type 1 diabetes mellitus: Furthermore, our data indicated that the administration of STZ-induced T1DM mice with sodium citrate buffer, insulin, adoptively transferred nBMCs or adoptively transferred dBMCs significantly decreased the level of serum CAT comparing to that in naive mice received sodium citrate buffer (0.8 ± 0.01 nmol/ml, 1.9 ± 0.03 nmol/ml, 1.81 ± 0.02 nmol/ml and 0.87 ± 0.00 nmol/ml, respectively versus 2.15 ± 0.04 nmol/ml) (Fig. 7B).