INS and type 1 diabetes mellitus: The data herein showed that the administration of STZ-induced T1DM mice with sodium citrate buffer, insulin, adoptively transferred nBMCs and adoptively transferred dBMCs significantly reduced the level of Islet antigen 2 protein (IA-2) comparing to that in naive mice received sodium citrate buffer (0.12 ± 0.01 pg/mg, 0.42 ± 0.01 pg/mg, 0.84 ± 0.01 pg/mg and 0.57 ± 0.01 pg/mg, respectively versus 1.01 ± 0.01 pg/mg) (Fig. 5E).