Admiration of STZ-induced T1DM mice with adoptively transferred nBMCs significantly increased the total number of splenocytes, while their administration with adoptively transferred dBMCs significantly decreased the splenocytes count comparing to that in STZ-induced T1DM mice treated with insulin (8.70 ± 0.20 × 106 and 4.70 ± 0.40 × 106, respectively versus 6.70 ± 0.40 × 106) (Fig. 3). This evidence concerns the gene INS and type 1 diabetes mellitus.