Khat was reported to induce phosphorylation and acetylation of p53 in both khat-treated acute myeloid leukemia cell lines sensitive (MOLM-13) or resistant (MV4-11) to khat-induced apoptosis, but an accumulation of the p53 full-length isoform was only seen in MOLM-1393. Here, TP53 is linked to acute myeloid leukemia.