They identified that epigenetic changes involving five miRNAs (hsa-mir-222, hsa-mir-221, hsa-mir-34a, hsa-mir-214, and hsa-mir-138-2) could be influencing the expression of genes such as BCL2, BCL2L11, PEG3, ALDH1A1, PLA2R1, TFCP2L1, RAB23, TK1, and CTSB, which may play roles in the development of FVPTC. Here, PEG3 is linked to follicular variant thyroid gland papillary carcinoma.