SPP1 and cyclic hematopoiesis: Compared with the CL + MH and ML + CH groups, the ML + MH group had higher expression levels of SPP1 (P < 0.01) (P < 0.01), IL2RB (P < 0.01) (P < 0.01), and CXCL9 (P < 0.01) (P < 0.01) (Fig. 6K).