MPC2 and neoplasm: Here, we show almost exclusive epithelial MPC1 and MPC2 localisation in both benign and malignant prostate (P < 0.05 for both; Fig. 3d), with tumour epithelial MPC2 density being significantly higher compared to the healthy tissue (P = 0.005; Fig. 3b, c), an observation also supported by bulk42, single-cell52,53, and spatial54 mRNA sequencing data presented in Fig. 3e–g.