CD4 and infection: This segregation was largely driven by increased frequencies of plasmacytoid dendritic cells (pDC, cluster 43), CD45RA+Foxp3+CD4+T cells (resting Tregs, cluster 7), and basophils (cluster 35) as well as decreased frequencies of memory CD4+T cells (clusters 4, 9, and 19) after infection (Fig. 2C).