Patients with obesity have altered immune system function, chronic inflammation, ACE2 highly expressed in adipose tissue, low vitamin D concentration, and overexpression of molecules associated with SARS‐CoV‐2 infection such as MCT4, alpha integrin, and activated T cell nuclear factor 1, among others [48, 49]. The gene discussed is ACE2; the disease is obesity due to melanocortin 4 receptor deficiency.