To study the effect of endogenous Cebpa reactivation in a mouse model of fibrosis, a single dose of 5 × 1011 genomic copies of AAV9-dgRNA_Cebpa or AAV9-control was injected intratracheally into the lungs of Cas9 mice 7 days after administering bleomycin (Figure 6J). The gene discussed is CEBPA; the disease is fibrosis.