On the other hand, rs1014754, influencing JPH2 expression positively in the adrenal gland (β = 0.552, P value = 3.47 × 10−8), similarly demonstrated the effect allele's (‘T’) positive association with hypertension (β = 0.0225, P value = 4.8 × 10−5). The gene discussed is JPH2; the disease is hypertensive disorder.