Therefore, it is believed that CHF might have certain antioxidant effect on patients with A on C. As an inflammatory signal that has been paid much attention to in recent years, NOD-like receptor protein-3 (NLRP3) inflammasome plays an important role in the occurrence and development of AKI (Li Y. et al., 2024; Xue et al., 2024). Here, NLRP3 is linked to acute kidney injury.