The transcriptomic analysis confirmed mRNA expression of classical epithelial markers (cytokeratins, claudins, EpCAM, E-cadherin) in the SW480 cancer cell mono-spheroids and typical fibroblast markers (ACTA2/α-SMA, FAP-α, PDGFR, and MRC2) in the fibroblast mono-spheroids. Here, PDGFRB is linked to cancer.